英文名稱 HHLA2
中文名稱 人內(nèi)源性逆轉(zhuǎn)錄病毒H長末端重復(fù)相關(guān)蛋白2抗體
別 名 Human endogenous retrovirus H long terminal repeat associating protein 2; HERV H LTR associating 2; HERV-H LTR-associating protein 2; HHLA 2; HHLA2; HHLA2_HUMAN; Human endogenous retrovirus-H long terminal repeat-associating protein 2.
研究領(lǐng)域 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
細(xì)胞定位 細(xì)胞膜
性 狀 Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HHLA2:231-330/414
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹 Human endogenous retroviruses (HERVs) are repetitive elements that are derived from ancient germline retroviral infections. Due to their ability to move and insert next to certain genes and alter expression patterns, HERVs have been linked to several chronic diseases such as nervous systemic diseases, cancer, autoimmune and connective tissue diseases. The HERV-H family is the most abundant HERV family and has been implicated in the expression of a variety of adjacent genes. Proteins belonging to the HERV-H family are divided into one major and two minor groups based on sequence divergence. As a member of the HERV-H family, HHLA2 (HERV-H LTR-associating protein 2) is a 414 amino acid single-pass type I membrane protein that contains one Ig-like C1-type (immunoglobulin-like) domain and two Ig-like V-type (immunoglobulin-like) domains. HHLA2 is primarily expressed in kidney, lung and intestinal tissues.
Subcellular Location:
Membrane; Single-pass type I membrane protein (By similarity).
Tissue Specificity:
Expressed in colon, small intestine, lung and kidney.
Similarity:
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.
Contains 2 Ig-like V-type (immunoglobulin-like) domains.
SWISS:
Q9UM44
Gene ID:
11148
Database links:
Entrez Gene: 11148 Human
Omim: 604371 Human
SwissProt: Q9UM44 Human
Unigene: 252351 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
| 產(chǎn)品圖片 |  Sample: MDA-MB-231(Human) Cell Lysate at 30 ug Primary: Anti-HHLA2 (ys-8419R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 60 kD  Sample: LOVO(Human) Cell Lysate at 30 ug A549(Human) Cell Lysate at 30 ug Primary: Anti-HHLA2 (ys-8419R) at 1/500 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 50kD |
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