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重組人白細(xì)胞介素-7受體a(CD127)蛋白

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產(chǎn)品編號(hào)bs-43043P
英文名稱Recombinant human IL-7R Alpha / CD127 protein, His (HEK293)
中文名稱重組人白細(xì)胞介素-7受體a(CD127)蛋白
別    名Interleukin-7 receptor subunit alpha; IL7R; CD 127; CD127; CD127 antigen; CDW127; IL 7R alpha; IL 7R; IL-7 receptor subunit alpha; IL-7R subunit alpha; IL-7R-alpha; IL-7RA; IL7RA; IL7Ralpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor; Interleukin 7 receptor isoform H5 6; IL7RA_HUMAN; Recombinant human IL-7R Alpha / CD127 protein, His (HEK293)  
理論分子量29.3kDa
檢測(cè)分子量40-70 kDa
性    狀Liquid
濃    度>0.5 mg/ml
物    種Human
序    列21-239/459
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)HEK293 cell
活性Yes
標(biāo)簽His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).

SWISS:
P16871

Gene ID:
3575

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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