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重組人自噬效應(yīng)蛋白Beclin 1

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產(chǎn)品編號(hào)bs-41365P
英文名稱Recombinant human Beclin 1 protein, N-His
中文名稱重組人自噬效應(yīng)蛋白Beclin 1
別    名Beclin-1; ATG6; beclin1; VPS30; Beclin 1 like protein 1; 4921513J16Rik; 5430417M23Rik; ATG6; BECLIN 1; BECN1; MGC6843; BECN1_HUMAN; Recombinant human Beclin 1 protein, N-His  
理論分子量38.8kDa
檢測(cè)分子量42 kDa
性    狀Lyophilized or Liquid
濃    度>0.5 mg/ml
物    種Human
序    列141-450/450
純    度>95% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
活性Not tested
標(biāo)簽N-His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Beclin 1 is the first identified mammalian gene to mediate autophagy and also has tumor suppressor and antiviral function. Autophagy, a process of bulk protein degradation through an autophagosomic lysosomal pathway, is important for differentiation, survival during nutrient deprivation, and normal growth control, and is often defective in tumor cells. Beclin 1 was originally isolated in a yeast two hybrid screen to identify Bcl 2 binding partners and maps to a tumor susceptibility locus on human chromosome 17q21 that is frequently monoallelically deleted in human breast, ovarian and prostate cancer. Beclin 1 encodes an evolutionarily conserved 52kDa coiled coil protein that is expressed in human muscle, epithelial cells and neurons.

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The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
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