產(chǎn)品編號 | bs-48035P |
英文名稱 | Recombinant human NGF-β protein (Active, HEK293) |
中文名稱 | 重組人神經(jīng)生長因子(活性的) |
別 名 | Beta-NGF Protein, Human;HSAN5 Protein, Human; NGFB Protein, Human;Recombinant human Nerve growth factor;Recombinant human NGF-β protein (Active, HEK293) |
檢測分子量 | 25 kDa |
性 狀 | Lyophilized powder |
濃 度 | >0.5 mg/ml |
物 種 | Human |
序 列 | 1-241/241 |
純 度 | >95% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | <0.5 EU/μg as determined by LAL. |
表達(dá)系統(tǒng) | HEK293 cell |
活性 | Yes |
標(biāo)簽 | Tag free |
保存條件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large complex consisting of three non-covalently linked subunits, α, β, and γ, among which, the β subunit, called β-NGF (beta-NGF), was demonstrated to exhibits the growth-stimulating activity of NGF protein. NGFB/beta-NGF gene is a member of the NGF-beta family and encodes a secreted protein that homodimerizes and is incorporated into a larger complex. NGF protein acts via at least two receptors on the surface of cells (TrkA and p75 receptors) to regulate neuronal survival, promote neurite outgrowth, and up-regulate certain neuronal functions such as mediation of pain and inflammation. Also, previous studies indicated that NGF may also have an important role in the regulation of the immune system. SWISS: P01138 Gene ID: 4803 |
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