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重組小鼠肌細(xì)胞生成素蛋白

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產(chǎn)品編號bs-42223P
英文名稱Recombinant mouse Myogenin protein, N-His
中文名稱重組小鼠肌細(xì)胞生成素蛋白
別    名MYOG_MOUSE; MYOG; BHLHC3; MYF4; Class C basic helix-loop-helix protein 3 (bHLHc3); Myogenic factor 4 (Myf-4); BHLHC3; MYF4; MYF 4;  
理論分子量27.4kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Mouse
序    列1-224/224
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽N-His
緩 沖 液20mM Tris-Hcl (pH=8.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹Myogenin is a member of a family of myogenic regulatory genes, which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors, which are essential for muscle development. Transfection of myogenin into multipotential mesodermal cells have been shown to convert the mesodermal cells to myoblasts. Expression of myogenin is restricted to cells of skeletal muscle origin. It is therefore a useful marker for tumors of the muscle lineage, being strongly expressed in alveolar rhabdomyosarcomas.

SWISS:
P12979

Gene ID:
17928

MYOG是肌肉中運(yùn)載氧的蛋白質(zhì),由153個(gè)氨基酸殘基組成,一種小分子蛋白質(zhì),含有血紅素,和血紅蛋白同源,與氧的結(jié)合能力介于血紅蛋白和細(xì)胞色素氧化酶之間,可幫助肌細(xì)胞將氧轉(zhuǎn)運(yùn)到線粒體。 肌細(xì)胞生成素在成肌分化過程中起著決定性的作用。在人體骨骼肌的胚胎發(fā)育過程中 ,肌細(xì)胞生成素伴隨成肌過程而呈高水平表達(dá)。MYOG主要由腎臟代謝并排泄,當(dāng)心肌或橫紋肌有損傷時(shí),肌紅蛋白便釋放入血中,血清中的肌紅蛋白即可明顯升高。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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