產(chǎn)品編號(hào) | bs-42054P |
英文名稱(chēng) | Recombinant mouse CD36 protein, C-His |
中文名稱(chēng) | 重組小鼠CD36蛋白 |
別 名 | Platelet glycoprotein 4; PAS-4; Platelet glycoprotein IV; Glycoprotein IIIb; GPIV; GPIIIB; GP3B; Leukocyte differentiation antigen CD36; PAS IV; Platelet collagen receptor; Fatty acid translocase; FAT; Thrombospondin receptor; CD_antigen: GP4; CD36_MOUSE. |
理論分子量 | 47.6kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >0.5mg/ml |
物 種 | Mouse |
序 列 | 30-439/472 |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | E.coli |
標(biāo)簽 | C-His |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 8M Urea and 0.3M L-Arg |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014] SWISS: Q08857 Gene ID: 12491 CD36屬一種多功能細(xì)胞膜受體,CD36參與長(zhǎng)鏈脂肪酸的吸附和調(diào)節(jié)細(xì)胞凋亡殘物的清理和巨噬細(xì)胞的吞噬作用, 屬于一種抗蛋白酶血小板膜表面糖蛋白。 CD36 廣泛在單核細(xì)胞、巨噬細(xì)胞、內(nèi)皮層細(xì)胞、血小板、紅細(xì)胞前板、脂肪細(xì)胞、肌肉細(xì)胞以及乳腺內(nèi)皮層細(xì)胞中有不同的表達(dá)。CD36抗原是血小板反應(yīng)素的配體,兩者結(jié)合后產(chǎn)生抑制腫瘤血管生成的效應(yīng)。 |
產(chǎn)品圖片 | |
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