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人細(xì)胞角蛋白17重組蛋白

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產(chǎn)品編號(hào)bs-42276P
英文名稱Recombinant human CK17 protein, N-Trx-His
中文名稱人細(xì)胞角蛋白17重組蛋白
理論分子量66.1kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
序    列1-432/432
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽N-Trx-His
緩 沖 液20mM Tris-Hcl (pH=8.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type pachyonychia congenita and steatocystoma multiplex. [provided by RefSeq, Aug 2008].

SWISS:
Q04695

Gene ID:
3872

結(jié)構(gòu)蛋白(Structural Proteins)
常用于腫瘤細(xì)胞的分化、增殖及轉(zhuǎn)移方面的研究。
產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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