| 產(chǎn)品編號(hào) | bs-42309P |
| 英文名稱 | Recombinant human IL-18 protein |
| 中文名稱 | 重組人IL18蛋白 |
| 別 名 | Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN |
| 理論分子量 | 18.2kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | >1mg/ml |
| 物 種 | Human |
| 序 列 | 37-193/193 |
| 純 度 | >90% as determined by SDS-PAGE |
| 純化方法 | AC |
| 內(nèi)毒素 | Not analyzed |
| 表達(dá)系統(tǒng) | E.coli |
| 標(biāo)簽 | Tag Free |
| 緩 沖 液 | 20mM Tris-Hcl (pH=8.0) with 2M Urea |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 | IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. SWISS: P97636 Gene ID: 29197 IL-18是巨噬細(xì)胞分泌的一個(gè)重要因子，它具有多種免疫功能，能誘導(dǎo)產(chǎn)生ＩＦＮγ，無(wú)論在病毒感染早期或特異性細(xì)胞免疫應(yīng)答效應(yīng)階段都會(huì)出現(xiàn)，因此IL-18主要參與免疫應(yīng)答及炎性細(xì)胞浸潤(rùn)的改變。Interleukin-18 又稱inteferon-gamma inducing factor(IGIF)，在輔助T細(xì)胞的應(yīng)答反應(yīng)中起重要作用。IL-18和IL-1一起，既參與先天免疫，又是后天免疫的構(gòu)成因素。 |
| 產(chǎn)品圖片 |  The purity of the protein is greater than 80% as determined by reducing SDS-PAGE. |
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