產(chǎn)品編號 | bs-42284P |
英文名稱 | Recombinant human KCNA3 protein, N-Trx&His |
中文名稱 | 重組人離子通道蛋白Kv1.3 |
別 名 | Potassium Channel Kv1.3; HGK 5; HGK5; HLK 3; HLK3; HPCN 3; HPCN3; HuKIII; KCNA 3; KCNA3; KV1.3; MK 3; MK3; PCN 3; PCN3; Potassium channel 3; Potassium voltage gated channel shaker related subfamily member 3; Potassium voltage gated channel subfamily A member 3; Type n potassium channel; Voltage gated potassium channel subunit Kv1.3. |
理論分子量 | 44.5kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/ml |
物 種 | Human |
序 列 | 1-234/575 |
純 度 | >90% as determined by SDS-PAGE |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
標(biāo)簽 | N-Trx&His |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008]. SWISS: P22001 Gene ID: 3738 |
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