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重組人前列腺特異性膜抗原蛋白

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產(chǎn)品編號bs-43139P
英文名稱Recombinant human Glutamate carboxypeptidase 2 protein, N-His (HEK293)
中文名稱重組人前列腺特異性膜抗原蛋白
別    名FOLH; PMSA; Cell growth inhibiting protein 27; FGCP; Folate hydrolase 1; folate hydrolase; Folate hydrolase prostate specific membrane antigen 1; FOLH 1; FOLH; Folylpoly gamma glutamate carboxypeptidase; GCP 2; GCP II; GCP2; GCPII; glutamate carboxylase II; Glutamate carboxypeptidase 2; glutamate carboxypeptidase II; Membrane glutamate carboxypeptidase; mGCP; N acetylated alpha linked acidic dipeptidase 1; N acetylated alpha linked acidic dipeptidase I; NAALAD 1; NAALAD1; NAALAdase; NAALADase I; prostate specific membrane antigen; PSM; pteroylpoly gamma glutamate carboxypeptidase; FOLH1_HUMAN.  
理論分子量80.6kDa
性    狀Lyophilized or Liquid
濃    度>0.5mg/ml
物    種Human
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達系統(tǒng)HEK293 cell
標簽C-His
緩 沖 液PBS (pH=7.4)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants. Subunit : Homodimer.

SWISS:
Q04609

Gene ID:
2346

產(chǎn)品圖片
The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
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