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重組人 FCGRT & B2M Heterodimer 蛋白

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產(chǎn)品編號bs-43201P
英文名稱Recombinant human FCGRT&B2M Heterodimer protein, C-His (HEK293)
中文名稱重組人 FCGRT & B2M Heterodimer 蛋白
理論分子量31.8&11.7kDa
性    狀Lyophilized or Liquid
濃    度>1mg/ml
物    種Human
純    度>90% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)HEK293 cell
標(biāo)簽C-His
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹FcRN present in the intestinal epithelium of neonatal mice and rats mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn animals to acquire passive immunity. FcRn (also designated FCGRT, Brambell receptor, FcRn ? chain, IgG Gc receptor and neonatal Fc-receptor) is comprised of a heavy chain and ∫-2-Microglobulin. FcRn heavy chain shows approximately 35% amino acid identity to an MHC class I molecule. FcRN localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal catabolism. This protection mechanism is a major constituent for ensuring IgG are the longest lived of all plasma proteins.

SWISS:
P55899

Gene ID:
2217

產(chǎn)品圖片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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