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重組SARS冠狀病毒2 Spike突變蛋白R(shí)BD(BQ.1.1/Omicron)

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產(chǎn)品編號(hào)bs-43157P
英文名稱(chēng)Recombinant SARS-Cov-2 Spike RBD protein (BQ.1.1/Omicron), His (HEK293)
中文名稱(chēng)重組SARS冠狀病毒2 Spike突變蛋白R(shí)BD(BQ.1.1/Omicron)
別    名SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2  
理論分子量26.7kDa
性    狀Lyophilized or Liquid
物    種SARS-Cov-2
純    度>90% as determined by SDS-PAGE
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)HEK293 cell
標(biāo)簽C-His
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.

SWISS:
P0DTC2

Gene ID:
43740568

產(chǎn)品圖片
Measured by its binding ability in a functional ELISA. Immobilized human ACE2, His-Avi Tag (Cat: bs-46001P) at 2μg/mL (100 μL/Well) can bind SARS-CoV-2 Spike RBD (BQ.1.1/Omicron), His Tag (Cat: bs-43157P), the EC50 is 34ng/mL.
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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