產(chǎn)品編號 | bs-42111P |
英文名稱 | Recombinant human CD86 protein, C-His |
中文名稱 | 重組人CD86蛋白 |
別 名 | CD28LG2; FUN1; LAB72; Activation B7 2 antigen; Activation B7-2 antigen 3; CD86_HUMAN; Activation B7-2 antigen; Activation B72 antigen; B lymphocyte activation antigen B7 2; B lymphocyte activation antigen B72; B-lymphocyte activation antigen B7-2 2; B-lymphocyte activation antigen B7-2; B7 2; B7 2 antigen; B7; B7-2; B7.2; B70; B72 antigen; BU63; CD 86; CD28 antigen ligand 2 2; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) 1, 2; CD86 antigen; CD86 molecule; CLS1; CTLA 4 counter receptor B7 2; CTLA 4 counter receptor B7.2; CTLA-4 counter-receptor B7.2 2, 3; CTLA4 counter receptor B72; Early T-cell costimulatory molecule 1; ETC-1; FUN 1; LAB72; Ly-58; Ly58; MB7; MB7-2; Membrane glycoprotein; MGC34413; T lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; TS/A-2. |
理論分子量 | 26.3kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | >1mg/m |
物 種 | Human |
純 度 | >90% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達系統(tǒng) | E.coli |
標簽 | C-His |
緩 沖 液 | 20mM Tris-Hcl (pH=8.0) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]. SWISS: P42081 Gene ID: 942 CD86是一個很重要要的輔助刺激分子,CD86作為CD28的輔助刺激分子,提供 T 細胞活化的輔助信號,它們之間的結(jié)合和隨后介導(dǎo)的信號轉(zhuǎn)導(dǎo)是 T 細胞和 APC 相互協(xié)作的重要分子基礎(chǔ)。 |
產(chǎn)品圖片 | |
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