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重組人血紅素氧合酶 1蛋白

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產(chǎn)品編號(hào)bs-42298P
英文名稱(chēng)Recombinant human Heme Oxygenase 1 protein, N-His
中文名稱(chēng)重組人血紅素氧合酶 1蛋白
別    名Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HO 1; HO-1; HO; HO1; Hsp32; bK286B10; D8Wsu38e; HMOX1_HUMAN.  
理論分子量32.7kDa
性    狀Liquid
濃    度>1mg/ml
物    種Human
序    列1-266/288
純    度>80% as determined by SDS-PAGE
純化方法AC
內(nèi)毒素Not analyzed
表達(dá)系統(tǒng)E.coli
標(biāo)簽N-His
緩 沖 液20mM Tris-Hcl (pH=9.0)
保存條件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項(xiàng)This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member.

SWISS:
P09601

Gene ID:
3162

血紅素氧合酶-1又稱(chēng)HSP-32( Heat Shock Protein 32)是一種血紅素降解的催化酶,在NADPH 和細(xì)胞色素P-450還原酶及分子氧作用下,HO-1催化血紅素降解為膽綠素、CO和鐵,前者還原成膽紅素后具有很強(qiáng)的抗氧化能力,后者是一種重要的信使分子。
近年研究發(fā)現(xiàn),熱休克蛋白32(HO-1)及其酶解產(chǎn)物膽紅素、CO、轉(zhuǎn)鐵蛋白共同發(fā)揮著抗炎、抗氧化、抑制細(xì)胞凋亡和改善組織微循環(huán)等作用,廣泛參與心、腦、肺、肝、腎等組織細(xì)胞的抗氧化應(yīng)激損傷,是機(jī)體最重要的內(nèi)源性保護(hù)體系之一,尤其是其組織器官的保護(hù)作用已逐漸成為目前研究的一個(gè)熱點(diǎn)。
產(chǎn)品圖片
The purity of the protein is greater than 70% as determined by reducing SDS-PAGE.
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