產(chǎn)品編號(hào) | bs-42298P |
英文名稱(chēng) | Recombinant human Heme Oxygenase 1 protein, N-His |
中文名稱(chēng) | 重組人血紅素氧合酶 1蛋白 |
別 名 | Heme oxygenase (decycling) 1; Heme oxygenase 1; Hemox; HMOX 1; Hmox; HMOX1; HO 1; HO-1; HO; HO1; Hsp32; bK286B10; D8Wsu38e; HMOX1_HUMAN. |
理論分子量 | 32.7kDa |
性 狀 | Liquid |
濃 度 | >1mg/ml |
物 種 | Human |
序 列 | 1-266/288 |
純 度 | >80% as determined by SDS-PAGE |
純化方法 | AC |
內(nèi)毒素 | Not analyzed |
表達(dá)系統(tǒng) | E.coli |
標(biāo)簽 | N-His |
緩 沖 液 | 20mM Tris-Hcl (pH=9.0) |
保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 | The hemeoxygenase-1 calls that the hemoglobin oxidizes to synthesize the enzyme again-1( hemeoxygenase-1, HO-1) is the catalyst enzyme that a kind of hemoglobin declines the solution, under the NADPH and the cell dye P-450 revivification enzymes and the member oxygen functions, the catalyst HO-1 hemoglobin declines the solution as the courage green vegetable, CO and irons, the former revivification has the very strong anti- to oxidize the ability after become the red vegetable of courage , the latter is a kind of important letter to make the member. SWISS: P09601 Gene ID: 3162 血紅素氧合酶-1又稱(chēng)HSP-32( Heat Shock Protein 32)是一種血紅素降解的催化酶,在NADPH 和細(xì)胞色素P-450還原酶及分子氧作用下,HO-1催化血紅素降解為膽綠素、CO和鐵,前者還原成膽紅素后具有很強(qiáng)的抗氧化能力,后者是一種重要的信使分子。 近年研究發(fā)現(xiàn),熱休克蛋白32(HO-1)及其酶解產(chǎn)物膽紅素、CO、轉(zhuǎn)鐵蛋白共同發(fā)揮著抗炎、抗氧化、抑制細(xì)胞凋亡和改善組織微循環(huán)等作用,廣泛參與心、腦、肺、肝、腎等組織細(xì)胞的抗氧化應(yīng)激損傷,是機(jī)體最重要的內(nèi)源性保護(hù)體系之一,尤其是其組織器官的保護(hù)作用已逐漸成為目前研究的一個(gè)熱點(diǎn)。 |
產(chǎn)品圖片 | |
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